Diabetic Nephropathy

Diabetic nephropathy also known as diabetic kidney disease is the chronic loss of kidney function occurring in those with diabetes mellitus. Protein loss in the urine due to damage to the glomeruli may become tremendous, and causes a low serum albumin with resulting generalized body swelling and result in the nephrotic syndrome. For some people, diabetic nephropathy can progress to chronic kidney disease and kidney failure. However, most people with diabetes do not develop kidney disease that progresses to kidney failure.

The main is to filter waste products and excess water from the bloodstream so that they can be excreted in the form of urine. This is carried out by a system of tubes and blood vessels known as nephrons. Inside the nephrons are tiny blood vessels called capillaries and tiny urine-collecting tubes. One of the major structures in the nephron is a group of blood vessels known as the glomerulus, which acts as a filter. Having high blood glucose levels can interfere with the function of the glomerulus. The filtering function of the kidneys doesn’t work properly and proteins start to leak from the blood into the urine.                                     

 

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