Genetics, Genomics & Endocrine Hereditary Disorders

Genetic and genomic sciences are revolutionizing the diagnosis and management of endocrine diseases. This track highlights advances in next-generation sequencing, polygenic risk scoring, gene expression analysis, and functional genomics that uncover hereditary predispositions to diabetes, thyroid disorders, obesity, adrenal syndromes, and rare metabolic diseases. Presenters will examine how pathogenic variants influence cellular pathways, endocrine organ development, and metabolic homeostasis. Case studies will demonstrate the role of genomic testing in early diagnosis, surveillance, and risk prediction.

The clinical application section explores how precision genomics is shaping modern endocrine practice. Discussions will include genetic counseling, targeted therapies for mutation-specific conditions, ethical considerations of genomic medicine, and evolving guidelines for screening families with hereditary endocrine tumor syndromes. Attendees will gain insights into genotype–phenotype correlations, novel gene discoveries, and the integration of multi-omic data into personalized treatment strategies. This track equips clinicians and researchers with the tools needed to incorporate genomic science into everyday endocrine care.

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